How will I receive MONJUVI?

MONJUVI will be given to you by your healthcare provider as an intravenous (IV) infusion into one of your veins. You will receive MONJUVI in a clinic or infusion center, so there’s no need to travel to a special cancer center.

Your doctor will also prescribe a 25-mg lenalidomide capsule for you to take orally once a day on days 1 to 21 of each treatment cycle, for the first 12 cycles.

Your healthcare provider will give you medicines before each infusion to decrease your chance of infusion reactions. If you do not have any reactions, your healthcare provider may decide that you do not need these medicines with later infusions. It is important to take these medicines as directed by your healthcare team.

MONJUVI infusion bag and lenalidomide pill

Following premedication, your first infusion will take about 1 ½ to 2 ½ hours. Your infusion time may vary if your healthcare team needs to make adjustments during treatment. Nurses and other healthcare professionals will be available to help you during your treatment.

Clock that reads 2 hours

After that, the infusion time may be shorter, but will be at least 90 minutes.

Your healthcare team may need to delay or completely stop treatment with MONJUVI if you have severe side effects.

Your treatment schedule

Each treatment cycle of MONJUVI lasts for 28 days. Your doctor will also prescribe a 25-mg lenalidomide capsule for you to take orally once a day on days 1 to 21 of each treatment cycle, for the first 12 cycles.

You will receive MONJUVI on 5 days during your first cycle.

 Cycle 1
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DAYS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
MONJUVI 12 mg/kg
Lenalidomide 25 mg daily

For your second and third cycles, you will receive MONJUVI on 4 days.

 Cycles 2 and 3
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DAYS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
MONJUVI 12 mg/kg
Lenalidomide 25 mg daily

After your first 3 cycles, you will receive MONJUVI once every 2 weeks.

 Cycles 4 to 12
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DAYS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
MONJUVI 12 mg/kg
Lenalidomide 25 mg daily

After 12 cycles, you will receive only MONJUVI.

 Cycles 13 and after
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DAYS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
MONJUVI 12 mg/kg

You may continue receiving MONJUVI for as long as your DLBCL responds to treatment, as directed by your healthcare team. Your healthcare provider will decide how many treatments you need.

Knowing and understanding your treatment schedule is important. You and your healthcare team can build a personalized schedule for your treatment with MONJUVI and lenalidomide.

If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment.

Common side effects

It is important for you to write down how you are feeling and any side effects you may be experiencing. Make sure you talk to your healthcare team about these side effects.

The most common side effects of MONJUVI include:

MONJUVI side effects include: feeling tired or weak, diarrhea, cough, fever, swelling of lower legs or hands, respiratory tract infection, and decreased appetite
MONJUVI side effects include: feeling tired or weak, diarrhea, cough, fever, swelling of lower legs or hands, respiratory tract infection, and decreased appetite

These are not all the possible side effects of MONJUVI. Call your doctor for medical advice about side effects.

Infusion-related reactions can occur at any time during treatment but are more frequent at the beginning of treatment. Your healthcare team may delay or completely stop your infusion and may also give you other medicines if you have severe side effects.

Tell your healthcare team right away if you get:

  1. Chills, flushing, headache, or shortness of breath during an infusion of MONJUVI
  2. A fever of 100.4 °F (38 °C) or above, or any bruising or bleeding
  3. A fever of 100.4 °F (38 °C) or above, or develop any signs or symptoms of an infection

Your healthcare provider will monitor your blood counts prior to each infusion and throughout your treatment with MONJUVI.

Talking with your healthcare team

Gather your thoughts and questions

There’s a lot you’ll want to know about treatment with MONJUVI. Each appointment you have is a good opportunity to ask questions. Write down your thoughts before you go to help you make the most of the time you spend with your doctor and healthcare team. Also, keep track of how you are feeling during your treatment, and make sure to discuss this at your next appointment.

  1. Here is a list of some common questions you may want to ask:

    • How often do I need to come in for appointments?
    • How will I know if MONJUVI is working?
    • What side effects should I be aware of?
    • What should I do if I experience side effects?
    • Is financial assistance available for MONJUVI?

Additional questions? Write down any questions that you want to ask your healthcare team at your next appointment.

Learn more about the resources available to
help you and your caregivers.

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